Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Jan;41(1):228-34.
doi: 10.1002/1097-0142(197801)41:1<228::aid-cncr2820410131>3.0.co;2-6.

The significance of vascular invasion and lymphocytic infiltration in invasive cervical cancer

J R van Nagell Jr, E S Donaldson, E G Wood, J C Parker Jr

The significance of vascular invasion and lymphocytic infiltration in invasive cervical cancer

J R van Nagell Jr et al. Cancer. 1978 Jan.

Abstract

Surgical specimens from 100 patients with stage I B cervical cancer undergoing radical hysterectomy and pelvic lymphadenectomy were reviewed with respect to vascular invasion and lymphoplasmacytic infiltration. Lymph nodes from these patients were classified morphologically according to the criteria proposed by Cottier. Vascular invasion was associated with a significant increase in nodal metastases and tumor recurrence particularly to extrapelvic sites. A marked lymphoplasmacytic infiltrate around tumor cells was associated with decreased nodal metastases and tumor recurrence. There was no significant relationship between the degree of lymphoplasmacytic infiltration of the primary tumor and regional lymph node morphology.

PubMed Disclaimer