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. 1981;37(9):978-9.
doi: 10.1007/BF01971790.

Increased urinary excretion of cyclic nucleotides in X-linked hypophosphatemic (Hyp) mice

Increased urinary excretion of cyclic nucleotides in X-linked hypophosphatemic (Hyp) mice

G M Kiebzak et al. Experientia. 1981.

Abstract

Hyp mice, a model for human X-linked hypophosphatemia, had elevated urinary cyclic AMP, cyclic GMP, and magnesium excretion compared to normal mice. The data suggest a renal origin of the urinary cyclic nucleotides. No significant differences in plasma cyclic AMP and cyclic GMP were observed between genotypes.

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