Increased urinary excretion of cyclic nucleotides in X-linked hypophosphatemic (Hyp) mice
- PMID: 6271566
- DOI: 10.1007/BF01971790
Increased urinary excretion of cyclic nucleotides in X-linked hypophosphatemic (Hyp) mice
Abstract
Hyp mice, a model for human X-linked hypophosphatemia, had elevated urinary cyclic AMP, cyclic GMP, and magnesium excretion compared to normal mice. The data suggest a renal origin of the urinary cyclic nucleotides. No significant differences in plasma cyclic AMP and cyclic GMP were observed between genotypes.
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