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. 1981 May 11;9(9):2195-206.
doi: 10.1093/nar/9.9.2195.

Conformational stability of alternating d (CG) oligomers in high salt solution

F Quadrifoglio, G Manzini, M Vasser, K Dinkelspiel, R Crea
Free PMC article

Conformational stability of alternating d (CG) oligomers in high salt solution

F Quadrifoglio et al. Nucleic Acids Res. .
Free PMC article

Abstract

The conformation of d (CG)n oligomers with n = 2,3 has been studied in aqueous solution in the presence of high salt concentration. A minimum n value of three is necessary to obtain a left-handed Z-helix. When d (CG)3 is flanked by three non Z-helicogenic alternating AT sequences the left-handed helix is unstable and a B-type conformation is obtained also at high salt concentration.

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