Comparative Study
[Genetic determination of the immune response of mice to cells of various histological types]
[Article in
Russian]
- PMID: 627344
Item in Clipboard
Comparative Study
[Genetic determination of the immune response of mice to cells of various histological types]
[Article in
Russian]
Genetika.
1978.
Abstract
The intensity of the immune response of cells in mice to strong transplantation antigens of the H-2 complex can depend on the histological type of cells taken for immunization. Splenic cells of C3H mice immunized the cells of BALB/c line better that cells of the non-lymphoid origin taken from the same donor. A reverse situation was observed in case of immunization by the same cells of the lines C57Bl/6 and A/He. It was shown by the analysis of the lines of the first generation derived from the crosses between the 3 lines studied and also by the analysis of these characters in mice born from the backcross, that these characters do not exhibit a simple Mendelian segregation.
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