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Comparative Study
. 1978;14(1):72-80.

[Genetic determination of the immune response of mice to cells of various histological types]

[Article in Russian]
V A Lavrovskiĭ, V Kh Viksler, Iu A Iurchenko, V A Razvorotnev
  • PMID: 627344
Comparative Study

[Genetic determination of the immune response of mice to cells of various histological types]

[Article in Russian]
V A Lavrovskiĭ et al. Genetika. 1978.

Abstract

The intensity of the immune response of cells in mice to strong transplantation antigens of the H-2 complex can depend on the histological type of cells taken for immunization. Splenic cells of C3H mice immunized the cells of BALB/c line better that cells of the non-lymphoid origin taken from the same donor. A reverse situation was observed in case of immunization by the same cells of the lines C57Bl/6 and A/He. It was shown by the analysis of the lines of the first generation derived from the crosses between the 3 lines studied and also by the analysis of these characters in mice born from the backcross, that these characters do not exhibit a simple Mendelian segregation.

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