Cloning overlapping DNA fragments from the B95-8 strain of Epstein-Barr virus reveals a site of homology to the internal repetition
- PMID: 6275132
- PMCID: PMC256713
- DOI: 10.1128/JVI.40.3.977-982.1981
Cloning overlapping DNA fragments from the B95-8 strain of Epstein-Barr virus reveals a site of homology to the internal repetition
Abstract
Overlapping, sheared DNA fragments from the B95-8 strain of Epstein-Barr virus were cloned in Charon 4A. Eleven recombinant phages plus one recombinant plasmid contained all of the sequences found in B95-8 virion DNA. Analysis of recombinant DNA molecules revealed a previously undetected site of homology to the internal repetition found in Epstein-Barr virus DNA. This site was adjacent to or at a site which was unstable when the recombinant DNA was propagated as phage DNA in procaryotic hosts.
Similar articles
-
Organization of the Epstein-Barr virus DNA molecule. II. Fine mapping of the boundaries of the internal repeat cluster of B95-8 and identification of additional small tandem repeats adjacent to the HR-1 deletion.J Virol. 1982 Jul;43(1):201-12. doi: 10.1128/JVI.43.1.201-212.1982. J Virol. 1982. PMID: 6286998 Free PMC article.
-
Epstein-Barr virus (B95-8) DNA VII: molecular cloning and detailed mapping.Proc Natl Acad Sci U S A. 1980 May;77(5):2999-3003. doi: 10.1073/pnas.77.5.2999. Proc Natl Acad Sci U S A. 1980. PMID: 6248879 Free PMC article.
-
Molecular cloning of the complete Epstein-Barr virus genome as a set of overlapping restriction endonuclease fragments.Nucleic Acids Res. 1981 Jul 10;9(13):2999-3014. doi: 10.1093/nar/9.13.2999. Nucleic Acids Res. 1981. PMID: 6269068 Free PMC article.
-
Variations among isolates of Epstein-Barr virus.Ann N Y Acad Sci. 1980;354:309-25. doi: 10.1111/j.1749-6632.1980.tb27974.x. Ann N Y Acad Sci. 1980. PMID: 6261649 Review. No abstract available.
-
Mapping of putative transforming sequences of EBV DNA.IARC Sci Publ (1971). 1978;(24 Pt 1):527-52. IARC Sci Publ (1971). 1978. PMID: 221358 Review.
Cited by
-
Lytic but not latent replication of epstein-barr virus is associated with PML and induces sequential release of nuclear domain 10 proteins.J Virol. 2000 Dec;74(24):11800-10. doi: 10.1128/jvi.74.24.11800-11810.2000. J Virol. 2000. PMID: 11090180 Free PMC article.
-
Two distant clusters of partially homologous small repeats of Epstein-Barr virus are transcribed upon induction of an abortive or lytic cycle of the virus.J Virol. 1983 Dec;48(3):731-43. doi: 10.1128/JVI.48.3.731-743.1983. J Virol. 1983. PMID: 6313969 Free PMC article.
-
Novel 12-O-tetradecanoylphorbol-13-acetate-responsive elements in the upstream sequence of the MS gene promoter of Epstein-Barr virus.J Virol. 1989 Dec;63(12):5062-8. doi: 10.1128/JVI.63.12.5062-5068.1989. J Virol. 1989. PMID: 2555542 Free PMC article.
-
Expression of a nuclear and a cytoplasmic Epstein-Barr virus early antigen after DNA transfer: cooperation of two distant parts of the genome for expression of the cytoplasmic antigen.Proc Natl Acad Sci U S A. 1984 Jul;81(14):4568-72. doi: 10.1073/pnas.81.14.4568. Proc Natl Acad Sci U S A. 1984. PMID: 6087334 Free PMC article.
-
Mutants of Epstein-Barr virus with a selective marker disrupting the TP gene transform B cells and replicate normally in culture.J Virol. 1993 Dec;67(12):7634-40. doi: 10.1128/JVI.67.12.7634-7640.1993. J Virol. 1993. PMID: 8230482 Free PMC article.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources