[Insensitivity of some rats to intraperitoneal injections of collagenase and trypsin]
[Article in
French]
- PMID: 6275964
Item in Clipboard
[Insensitivity of some rats to intraperitoneal injections of collagenase and trypsin]
[Article in
French]
C R Seances Soc Biol Fil.
1981.
Abstract
In the rat peritoneal injections of collagenase or trypsin give rise to severe lesions. In our experience 20% of the animals remain intact. The frequency of lesions increases with older and heavier subjects. Moreover 25% of the rats who remained free of lesions after a first injection of collagenase resist to a second one. This shows that they are strongly protected against the enzyme. The exact nature and location of this protective mechanism are not known.
Similar articles
-
[Proteasic polyseritis: effects of intraperitoneal injections of collagenase, alone or together with the administration of trypsin].C R Seances Soc Biol Fil. 1978;172(4):718-24. C R Seances Soc Biol Fil. 1978. PMID: 218702 French.
-
[Comparative studies on the cultivability and morphology of rat hepatocytes isolated by trypsin or collagenase].Pharmazie. 1991 Jun;46(6):445-7. Pharmazie. 1991. PMID: 1662400 German.
-
[Anacollagenase by the action of amitriptyline on Clostridium histolyticum collagenase].C R Seances Soc Biol Fil. 1991;185(1-2):78-83. C R Seances Soc Biol Fil. 1991. PMID: 1666017 French.
-
Identification of collagenase-sensitive constituents of rat liver nuclear matrices.Biochem Int. 1984 Jan;8(1):165-70. Biochem Int. 1984. PMID: 6089815
-
Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.Int J Toxicol. 2007;26 Suppl 1:3-106. doi: 10.1080/10915810601163939. Int J Toxicol. 2007. PMID: 17365137 Review.