Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1981;70(1):21-32.
doi: 10.1007/BF01320790.

Thermal stability of foot-and-mouth disease virus

T R Doel, P J Baccarini
Comparative Study

Thermal stability of foot-and-mouth disease virus

T R Doel et al. Arch Virol. 1981.

Abstract

The thermal stabilities of 146S component of seven strains of foot-and-mouth disease virus were found to differ considerably. Inactivation of infectivity with acetylethyleneimine (AEI) reduced the thermal stabilities of all but one of the viruses. Treatment of AEI inactivated and control virus preparations with glutaraldehyde stabilized 146S particles to a considerable extent, whereas treatment with dimethyl suberimidate was less effective. In similar experiments with 75S, natural empty particles, the thermal stabilities were lower than those of the corresponding 146 S particles. Treatment of 75S particles with AEI appeared to have no direct effect on the protein-protein interactions involved in 75S capsid integrity. As with 146S particles, glutaraldehyde stabilized 75S particles.

PubMed Disclaimer

References

    1. Acta Pathol Microbiol Scand. 1954;35(4):388-95 - PubMed
    1. Arch Gesamte Virusforsch. 1972;39(1):274-83 - PubMed
    1. Nature. 1961 Dec 23;192:1163-4 - PubMed
    1. J Hyg (Lond). 1963 Sep;61:345-51 - PubMed
    1. Annu Rev Biochem. 1977;46:523-51 - PubMed

Publication types

LinkOut - more resources