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. 1981;4(3-4):293-300.
doi: 10.1016/0147-9571(81)90015-1.

[Evolution of anti-rota virus antibodies in the milk of cows treated in the last month of pregnancy either by adjuvated rotavirus vaccine or by the adjuvant fraction of the vaccine (author's transl)]

[Article in French]
E Van Opdenbosch, G Wellemans, R Strobbe, D L De Brabander, C V Boucqué

[Evolution of anti-rota virus antibodies in the milk of cows treated in the last month of pregnancy either by adjuvated rotavirus vaccine or by the adjuvant fraction of the vaccine (author's transl)]

[Article in French]
E Van Opdenbosch et al. Comp Immunol Microbiol Infect Dis. 1981.

Abstract
in English, French

The authors describe the evolution of the secretion of anti-Rotavirus antibodies vaccine given three weeks before and repeated at the moment of parturition. Rota virus antibodies were detected at a high level during the three months test period with the Indirect Immunofluorescence Test, the seroneutralisation test and the immunofluorescence test. The four untreated animals excreted only rota-antibodies till day 6 post partum. Seroneutralising antibodies were detected in the milk of the vaccinated animals at a level of 10–50% of the colostral level till day 90. The aspecific stimulation of the excretion of anti-Rotavirus antibodies in the milk after inoculation of the only adjuvant fraction of the vaccine is confirmed. The excretion level, however, was significantly lower than after Rotavirus vaccination.

Les auteurs ont observé que les anticorps SN (neutralisants), IFI (Immunofluorescence indirecte) et ID (Immunodiffusion) anti-Rota sont excrétés à un haut niveau dans le lait après vaccination des vaches à l'aide d'un vaccin Rota adjuvé, administré 3 semaines avant la mise-bas avec un rappel au moment du part. L'excrétion se maintient pendant au moins trois mois à un niveau se situant entre 10 et 50% du taux colostral. Ce travail confirme également la stimulation aspécifique de l'excretion d'anticorps anti-Rotavirus dans le lait par l'inoculation de la seule fraction adjuvante du vaccin. Cette excrétion est cependant moindre que celle induite par la vaccination à l'aide d'un vaccin anti-Rotavirus.

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References

    1. Ellens D.J., Leeuw P.W., Straver P.J. The detection of Rota-virus specific antibody in colostrum and milk by ELISA. Ann. Rec. Vet. 1978;9:337–342. - PubMed
    1. Mebus C.A., Kono L., Underdahl N.R., Twiehaus M.J. Cell culture propagation of a neonatal calf diarrhoea (scours) virus. Can. Vet. J. 1971;12:69–72. - PMC - PubMed
    1. Snodgrass D.R., Fahey K.J., Wells P.W., Campbell I., Whitelaw A. Passive immunity of calf rotavirus infection: maternal vaccination increases and prolongs immunoglobulin GI antibody secretion in milk. Infect. Immunity. 1971;28(2):344–349. - PMC - PubMed
    1. Van Opdenbosch E., Dekegel E., Wellemans G. De immunodiffusietest voor het opsporen van het Rotavirus in meststalen en darmfragmenten. Vl. Dierg. Tijdschr. 1978;47:276–291.
    1. Van Opdenbosche E., Wellemans G., Dekegel D., Strobbe R. Neonatal calf diarrhoea: a complex viral etiology. Vl. Dierg. Tijdschr. 1979;48(6):512–526.

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