doi: 10.1677/joe.0.0760187.
Precocious 'feminization' of rat liver enzymes in the presence of ectopic pituitary tissue
- PMID: 627814
- DOI: 10.1677/joe.0.0760187
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Precocious 'feminization' of rat liver enzymes in the presence of ectopic pituitary tissue
J Endocrinol.
1978 Feb.
Abstract
The presence of ectopic pituitary tissue (derived from an adult rat) in prepubertal male and female rats caused the immature, masculine-type hepatic steroid metabolism to develop into female-type metabolism. It is concluded that the hypothalamus-pituitary system controls the ontogenesis of sex-dependent steroid metabolism in rat liver.
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