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. 1981;184(3):536-8.
doi: 10.1007/BF00352535.

Primary structure of Escherichia coli RNA polymerase nucleotide substitution in the beta subunit gene of the rifampicin resistant rpoB255 mutant

Ovchinnikov YuA, G S Monastyrskaya, V V Gubanov, V M Lipkin, E D Sverdlov, I F Kiver, I A Bass, S Z Mindlin, O N Danilevskaya, R B Khesin

Primary structure of Escherichia coli RNA polymerase nucleotide substitution in the beta subunit gene of the rifampicin resistant rpoB255 mutant

Ovchinnikov YuA et al. Mol Gen Genet. 1981.

Abstract

The transducing phage lambda dsupM814 and the plasmid pIB1830 containing the wild-type rpoB gene have been constructed and the primary structure of the gene's central fragment has been established. In contrast with the wild-type, the gene of the rpoB255 mutant, whose primary structure has been published, was found to contain an A.T. leads to T.A. transversion entailing the substitution of a valine residue for the aspartic acid residue (516) of the wild-type beta subunit.

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References

    1. Genetika. 1973 Dec;9(12):84-94 - PubMed
    1. Biochimie. 1971;53(4):507-16 - PubMed
    1. FEBS Lett. 1970 Dec;11(3):165-168 - PubMed
    1. Mol Gen Genet. 1980 Feb;177(3):527-33 - PubMed
    1. Mol Gen Genet. 1973 Mar 1;121(2):181-96 - PubMed

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