[Structure of human globin genes]

Abstract

An attempt has been undertaken to review the present data on the structure of alpha- and beta-like human globin gene families, their quantity in a cell genome, intergene spacers, evolution and common features and differences in globin genes sequences. Some other questions, concerning the regulation of globin genes expression, transcription, structure and processing of primary transcripts, the structure of globin messenger RNAs have been also discussed.