[Effectiveness of alizapride against emesis in infants and children (author's transl)]

Abstract

The effectiveness of alizapride against vomiting was studied in a group of 40 patients including neonates, infants and children. Patients were hospitalized in a surgical ward. 2 to 8 mg/kg/24 h were given orally. Vomiting ceased in 75% of the cases. Optimal results were obtained with 4 to 5.6 mg/kg/24 h. With alizapride symptoms abated in all patients. Operative conditions were improved for those who needed surgery. In addition, nausea was relieved in 100% of cases and regurgitations in 67.7%. Our study shows that alizapride is a reliable drug with a short time lag and no side-effects. We conclude that it can be used against vomiting in pediatric patients.