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. 1976 Nov 26;214(1):61-9.
doi: 10.1007/BF00313489.

Erythrocyte ghosts (Na+ + K+) ATPase activity in Duchenne's dystrophy and myotonia

Erythrocyte ghosts (Na+ + K+) ATPase activity in Duchenne's dystrophy and myotonia

I Niebrój-Dobosz. J Neurol. .

Abstract

In Duchenne muscular dystrophy the activity of (Na+ + K+)ATPase in erythrocyte ghosts is reduced and its reaction to ouabain is paradoxical both in low sodium and high sodium systems. No such changes were seen in a case of Becker dystrophy, in limb-girdle dystrophy, and in neurogenic atrophy of muscles. In myotonic dystrophy and congenital myotonia the activity of ATPase and its inhibition by ouabain were depressed.

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