Erythrocyte ghosts (Na+ + K+) ATPase activity in Duchenne's dystrophy and myotonia
- PMID: 62828
- DOI: 10.1007/BF00313489
Erythrocyte ghosts (Na+ + K+) ATPase activity in Duchenne's dystrophy and myotonia
Abstract
In Duchenne muscular dystrophy the activity of (Na+ + K+)ATPase in erythrocyte ghosts is reduced and its reaction to ouabain is paradoxical both in low sodium and high sodium systems. No such changes were seen in a case of Becker dystrophy, in limb-girdle dystrophy, and in neurogenic atrophy of muscles. In myotonic dystrophy and congenital myotonia the activity of ATPase and its inhibition by ouabain were depressed.