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Comparative Study
. 1982 Mar;393(1):121-2.
doi: 10.1007/BF00582404.

On the changes of the time course of the end-plate current during repetitive stimulation

F Ruzzier, F Di Gregorio, M Scuka
Comparative Study

On the changes of the time course of the end-plate current during repetitive stimulation

F Ruzzier et al. Pflugers Arch. 1982 Mar.

Abstract

In a previous study it was observed that prolonged repetitive stimulation (10.s-1) markedly lengthened the time course of the end-plate current. In order to investigate whether this effect could be due to a more dispersed release of the mediator or to a decreased clearance of the mediator from the synaptic cleft, the rise time of the end-plate current and of the miniature end-plate current were analyzed. The results show that presynaptic factors may be involved.

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References

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