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. 1982 May;79(9):3024-7.
doi: 10.1073/pnas.79.9.3024.

Human gamma-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis

A Grubb, H Löfberg

Human gamma-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis

A Grubb et al. Proc Natl Acad Sci U S A. 1982 May.

Abstract

The amino acid sequence of human gamma-trace, a basic microprotein without known function, was determined by automated Edman degradations of the carboxymethylated polypeptide chain and of fragments obtained by cyanogen bromide treatment and tryptic digestion after blocking of lysine residues. The single polypeptide chain contained 120 residues, and the calculated Mr was 13,260. A proline residue at position 3 was partly hydroxylated. The presence of gamma-trace in a significant proportion of the cells in the anterior lobe of simian and human pituitary glands was demonstrated by immunohistochemical procedures with a rabbit antiserum against human gamma-trace. The tissue localization and amino acid sequence of gamma-trace indicated that this protein is connected with the peptidergic gastroenteropancreatic neuroendocrine system.

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References

    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. Biochem J. 1968 Sep;109(2):312-4 - PubMed
    1. Eur J Biochem. 1967 Mar;1(1):80-91 - PubMed
    1. Nature. 1979 Mar 29;278(5703):423-7 - PubMed
    1. Biochem Biophys Res Commun. 1979 Feb 14;86(3):613-9 - PubMed

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