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. 1982 Jul;66(7):1567-9.

Phase II trial of doxorubicin therapy for advanced islet cell carcinoma

C G Moertel, P T Lavin, R G Hahn
  • PMID: 6284361

Phase II trial of doxorubicin therapy for advanced islet cell carcinoma

C G Moertel et al. Cancer Treat Rep. 1982 Jul.

Abstract

Twenty evaluable patients with advanced islet cell carcinoma were treated with doxorubicin at a dosage of 60 mg/m2 every 3-4 weeks. Toxicity was clinically tolerable and characteristic of doxorubicin therapy. Although all patients had previously been treated with other chemotherapy regiments, four (20%) had objective therapeutic responses persisting for 2-301/2 months. Doxorubicin has definite therapeutic activity in islet cell carcinoma and is currently being evaluated in combination chemotherapy regimens.

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