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. 1982 Jul 20;73(1A):4-6.
doi: 10.1016/0002-9343(82)90054-7.

Acyclovir chemistry and spectrum of activity

Acyclovir chemistry and spectrum of activity

H J Schaeffer. Am J Med. .

Abstract

Most antiviral agents with activity against the herpes group of viruses belong to a class of compounds known as nucleosides. Recently, an acyclic analog of a natural nucleoside has been found to have high activity against the herpes virus. This compound, called generically acyclovir, is 9-(hydroxymethyl)guanine. Its spectrum of antiviral activity is described.

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