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. 1982 May;21(5):836-7.
doi: 10.1128/AAC.21.5.836.

Capillary agar diffusion assay for measuring metronidazole in human gingival crevice fluid

F Notten, A Koek-Van Oosten, F Mikx

Capillary agar diffusion assay for measuring metronidazole in human gingival crevice fluid

F Notten et al. Antimicrob Agents Chemother. 1982 May.

Abstract

An agar diffusion assay in capillaries, with Fusobacterium nucleatum M2 as the indicator strain, has been developed to measure metronidazole concentrations in gingival crevice fluid. The assay allows the measurement of 1.9 micrograms of metronidazole per ml in sample amounts of 0.6 microliters.

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