Rescue and serotypic characterization of noncultivable human rotavirus by gene reassortment
- PMID: 6286486
- PMCID: PMC347496
- DOI: 10.1128/iai.37.1.104-109.1982
Rescue and serotypic characterization of noncultivable human rotavirus by gene reassortment
Abstract
Thirty-three of 50 noncultivable human rotavirus strains from a variety of locations were successfully rescued by gene reassortment. The serotype of each of the 33 strains was investigated by a qualitative cytopathic effect neutralization assay. Nineteen strains resembled the previously characterized human rotavirus serotype Wa, whereas three strains were serologically related to the DS-1 strain. Eleven strains appeared to be serotypically distinct from the Wa and DS-1 strains and thus apparently represent one or more new human rotavirus serotypes.
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