Enhancement of human rotavirus infectivity in a monkey kidney cell line by human expressed breast milk
- PMID: 6286865
- DOI: 10.1002/jmv.1890090409
Enhancement of human rotavirus infectivity in a monkey kidney cell line by human expressed breast milk
Abstract
Eight of forty (20%) human expressed breast milks enhanced the infectivity of human rotavirus (HRV) when assayed by immunofluorescence in a monkey kidney cell line (LLC-MK2). This enhancement was demonstrated with two HRV strains, one derived from a fecal specimen of a child with acute gastroenteritis, the other a tissue culture adapted strain. The phenomenon could have important implications in the pathogenesis of HRV infections and in future vaccine programs.
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