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. 1982;9(4):307-10.
doi: 10.1002/jmv.1890090409.

Enhancement of human rotavirus infectivity in a monkey kidney cell line by human expressed breast milk

Enhancement of human rotavirus infectivity in a monkey kidney cell line by human expressed breast milk

B M Totterdell et al. J Med Virol. 1982.

Abstract

Eight of forty (20%) human expressed breast milks enhanced the infectivity of human rotavirus (HRV) when assayed by immunofluorescence in a monkey kidney cell line (LLC-MK2). This enhancement was demonstrated with two HRV strains, one derived from a fecal specimen of a child with acute gastroenteritis, the other a tissue culture adapted strain. The phenomenon could have important implications in the pathogenesis of HRV infections and in future vaccine programs.

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