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. 1982 Jul;43(1):1-7.
doi: 10.1128/JVI.43.1.1-7.1982.

Unique features of retrovirus expression in F/St mice

H C Morse 3rd, C A Kozak, R A Yetter, J W Hartley

Unique features of retrovirus expression in F/St mice

H C Morse 3rd et al. J Virol. 1982 Jul.

Abstract

F/St mice are unique in producing high levels of both ecotropic and xenotropic murine leukemia virus. The high ecotropic virus phenotype is determined by three or more V (virus-inducing) loci. A single locus for inducibility of xenotropic murine leukemia virus was mapped to chromosome 1 close to, but possibly not allelic to, Bxv-1. Although the high ecotropic virus phenotype is phenotypically dominant, the high xenotropic virus phenotype was recessive in all crosses tested. Suppression of xenotropic murine leukemia virus is governed by a single gene which is not linked to the xenotropic V locus.

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