Comparative Study
doi: 10.1126/science.6287580.
Numbers of receptor sites from Scatchard graphs: facts and fantasies
- PMID: 6287580
- DOI: 10.1126/science.6287580
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Comparative Study
Numbers of receptor sites from Scatchard graphs: facts and fantasies
Science.
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Abstract
Data for ligand and receptor binding presented in the format of a Scatchard graph are compared with the same data shown as bound ligand plotted against the logarithm of free ligand. From this comparison it is apparent that extrapolations in the Scatchard graph to yield total number of receptor sites are generally not correct.
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