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. 1982;171(1):53-7.
doi: 10.1007/BF02122707.

In vitro stimulation of lymphocytes by different strains of cytomegalovirus

L Gärtner, J A Wilhelm, R Czieschnek

In vitro stimulation of lymphocytes by different strains of cytomegalovirus

L Gärtner et al. Med Microbiol Immunol. 1982.

Abstract

The in vitro stimulation of lymphocytes from 15 healty adult donors by 5 different stains of CMV resulted in a positive stimulation ratio of lymphocytes from CMV seropositive donors with each of the 5 different strains. Differences in the absolute strength of the response was observed among the 5 strains for each individual, but we concluded that the use of antigen prepared with 1 strain of CMV is sufficient to obtain a positive or negative result. A maximum value for the in vitro lymphocyte stimulation test, however, will only be obtained using different antigen concentrations from several different CMV strains simultaneously.

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