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Comparative Study
. 1982 Jul 24;10(14):4203-14.
doi: 10.1093/nar/10.14.4203.

Immunoglobulin switch region-like sequences in Drosophila melanogaster

Y Sakoyama, Y Yaoita, T Honjo
Comparative Study

Immunoglobulin switch region-like sequences in Drosophila melanogaster

Y Sakoyama et al. Nucleic Acids Res. .

Abstract

We found immunoglobulin switch (S) region-like sequences in DNAs of wide variety of organisms including sea urchin, yeast and Drosophila that do not produce immunoglobulins. DNA fragments carrying Smu-like sequences were cloned from Drosophila and the nucleotide sequence of a clone is almost identical to that of the mouse Smu region. Restriction fragments of Drosophila Smu-like sequences and their flanking regions seem to vary among Drosophila species. Possible evolutionary significance of the Smu-like sequence in invertebrates was discussed.

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References

    1. Gene. 1980 Oct;11(1-2):117-27 - PubMed
    1. Nucleic Acids Res. 1980 Sep 11;8(17):3933-45 - PubMed
    1. Proc Natl Acad Sci U S A. 1980 Nov;77(11):6734-8 - PubMed
    1. Nucleic Acids Res. 1980 Dec 20;8(24):5983-91 - PubMed
    1. Cell. 1981 Feb;23(2):357-68 - PubMed

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