Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Oct 22;218(4570):381-4.
doi: 10.1126/science.6289440.

Herpes simplex virus type-1 glycoprotein D gene: nucleotide sequence and expression in Escherichia coli

R J Watson, J H Weis, J S Salstrom, L W Enquist

Herpes simplex virus type-1 glycoprotein D gene: nucleotide sequence and expression in Escherichia coli

R J Watson et al. Science. .

Abstract

The protein coding region of the herpes simplex virus type-1 glycoprotein D (gD) gene was mapped, and the nucleotide sequence was determined. The predicted amino acid sequence of the gD polypeptide was found to contain a number of features in common with other virus glycoproteins. Insertion of this protein coding region into a bacterial expressor plasmid enabled synthesis in Escherichia coli of an immunoreactive gD-related polypeptide. The potential of this system for preparation of a type-common herpes simplex virus vaccine is discussed.

PubMed Disclaimer

Publication types

Associated data

LinkOut - more resources