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. 1982 Nov 12;218(4573):693-5.
doi: 10.1126/science.6291151.

Cotransmitters in the motor nerves of the guinea pig vas deferens: electrophysiological evidence

P Sneddon, D P Westfall, J S Fedan

Cotransmitters in the motor nerves of the guinea pig vas deferens: electrophysiological evidence

P Sneddon et al. Science. .

Abstract

The contractile response of the guinea pig vas deferens to motor nerve stimulation is biphasic. The first phase is antagonized by the specific adenosine triphosphate-receptor antagonist arylazido aminoproprionyl adenosine triphosphate (ANAPP3), and the second by the alpha-receptor antagonist prazosin. The underlying electrical event, the excitatory junction potential, is also blocked by ANAPP3, but not by prazosin.

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