Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Dec;58(6):381-6.
doi: 10.1136/sti.58.6.381.

Preparation and immunogenicity of vaccine Ac NFU1 (S-) MRC towards the prevention of herpes genitalis

G R Skinner, C B Woodman, C E Hartley, A Buchan, A Fuller, J Durham, M Synnott, J C Clay, J Melling, C Wiblin, J Wilkins

Preparation and immunogenicity of vaccine Ac NFU1 (S-) MRC towards the prevention of herpes genitalis

G R Skinner et al. Br J Vener Dis. 1982 Dec.

Abstract

A subunit antigenoid vaccine, Ac NFU1 (S-) MRC, was used to prevent primary herpes genitalis in 60 subjects considered to be at risk of this infection. There was no evidence of serious local or general side effects. Neutralising antibody responses were detected in 59% and 90% of subjects receiving the low and high doses of vaccine respectively; immunoprecipitating antibody was detected at a lower frequency, namely in 23% and 43% of subjects receiving the low and high doses respectively. After a mean follow-up period of 18 months none of the vaccinated subjects contracted herpes genitalis after completing the vaccination course.

PubMed Disclaimer

References

    1. Cancer. 1966 Jul;19(7):1026-31 - PubMed
    1. J Gen Virol. 1971 Aug;12(2):195-7 - PubMed
    1. J Gen Virol. 1973 May;19(2):217-33 - PubMed
    1. Am J Epidemiol. 1973 Aug;98(2):77-87 - PubMed
    1. J Hyg Epidemiol Microbiol Immunol. 1973;17(2):237-49 - PubMed