Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Nov 25;10(22):7197-210.
doi: 10.1093/nar/10.22.7197.

Cloning and nucleotide sequencing of the bovine growth hormone gene

R P Woychik, S A Camper, R H Lyons, S Horowitz, E C Goodwin, F M Rottman

Cloning and nucleotide sequencing of the bovine growth hormone gene

R P Woychik et al. Nucleic Acids Res. .

Abstract

A gene coding for bovine growth hormone was isolated from a bovine genomic library. The nucleotide sequence of the coding regions of the gene was found to be identical with that of a nearly full-length growth hormone cDNA clone. The gene sequence is approximately 1800 bp in length and contains four intervening sequences. The second intervening sequence of 227 nucleotides does not contain a repetitive element similar to that observed in the rat growth hormone gene. A comparison of the 5' and 3' flanking and untranslated regions of the bovine, human and rat growth hormone genes revealed many areas of highly conserved sequence. Especially noteworthy was the observation that all three genes had a 38 nucleotide homologous sequence within their 5' flanking regions located about 100 bp upstream from their transcription initiation sites.

PubMed Disclaimer

References

    1. J Cell Biol. 1970 Oct;47(1):61-70 - PubMed
    1. FEBS Lett. 1973 Sep 1;35(1):11-4 - PubMed
    1. J Mol Biol. 1975 Nov 5;98(3):503-17 - PubMed
    1. Nature. 1976 Sep 16;263(5574):211-4 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 May;74(5):1816-20 - PubMed

Associated data