5' viral and human cellular sequences corresponding to the transforming gene of simian sarcoma virus
- PMID: 6297002
- DOI: 10.1126/science.6297002
5' viral and human cellular sequences corresponding to the transforming gene of simian sarcoma virus
Abstract
The 5' nucleotide sequences of the transforming gene of simian sarcoma virus (v-sis) and its human cellular homolog (c-sis) were compared. A short homology was found between helper virus and cellular DNA sequences at the junction of v-sis and c-sis, which may have had a role in the original recombination event leading to the generation of simian sarcoma virus.
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