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. 1983 Feb 4;219(4584):503-5.
doi: 10.1126/science.6297002.

5' viral and human cellular sequences corresponding to the transforming gene of simian sarcoma virus

5' viral and human cellular sequences corresponding to the transforming gene of simian sarcoma virus

S F Josephs et al. Science. .

Abstract

The 5' nucleotide sequences of the transforming gene of simian sarcoma virus (v-sis) and its human cellular homolog (c-sis) were compared. A short homology was found between helper virus and cellular DNA sequences at the junction of v-sis and c-sis, which may have had a role in the original recombination event leading to the generation of simian sarcoma virus.

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