doi: 10.1126/science.6297010.
Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells
- PMID: 6297010
- DOI: 10.1126/science.6297010
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Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells
Science.
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Abstract
Ammonium chloride, a lysosomotropic agent that raises intralysosomal pH, reduces the yield of reovirus during infection of mouse L cells. Subsequent removal of ammonium chloride results in the rapid establishment of a persistent infection.
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