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. 1982 Dec 20;10(24):8285-95.
doi: 10.1093/nar/10.24.8285.

Comparison of the amino acid sequence of the major immunogen from three serotypes of foot and mouth disease virus

A J Makoff, C A Paynter, D J Rowlands, J C Boothroyd
Free PMC article

Comparison of the amino acid sequence of the major immunogen from three serotypes of foot and mouth disease virus

A J Makoff et al. Nucleic Acids Res. .
Free PMC article

Abstract

Cloned cDNA molecules from three serotypes of FMDV have been sequenced around the VP1-coding region. The predicted amino acid sequences for VP1 were compared with the published sequences and variable regions identified. The amino acid sequences were also analysed for hydrophilic regions. Two of the variable regions, numbered 129-160 and 193-204 overlapped hydrophilic regions, and were therefore identified as potentially immunogenic. These regions overlap regions shown by others to be immunogenic.

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