Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Feb;50(1):29-32.
doi: 10.1111/j.1464-410x.1978.tb02761.x.

Prednimustine therapy for advanced prostatic cancer

R Catane, J H Kaufman, S Madajewicz, A Mittelman, G P Murphy

Prednimustine therapy for advanced prostatic cancer

R Catane et al. Br J Urol. 1978 Feb.

Abstract

23 patients with advanced, hormonal-resistant, prostatic cancer were treated with daily oral prednimustine--a combination of prednisolone and chlorambucil. 8 patients (35%) subjectively responded with disappearance of skeletal pain and improvement in appetite, weight and sense of well being. 3 patients had objective evidence of tumour regression. Clinical toxicity was moderate, and only occasional myelosuppression was encountered. The ease of administration and predictable toxicity of prenimustine make it a potentially useful agent, alone or in combination, for advanced prostatic cancer.

PubMed Disclaimer

Publication types

LinkOut - more resources