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. 1983 Jan 31;35(1):71-7.
doi: 10.1016/0304-3940(83)90529-3.

Voltage-sensitive Na+ channels in the neurohypophysis of the rat as demonstrated by 125I-labelled scorpion toxin

H D Dellmann, J A Boudier, F Couraud, P Cau, J L Boudier

Voltage-sensitive Na+ channels in the neurohypophysis of the rat as demonstrated by 125I-labelled scorpion toxin

H D Dellmann et al. Neurosci Lett. .

Abstract

Fresh rat neural lobe slices were incubated in the presence of [125I] alpha-scorpion toxin (ScTX), a specific marker of Na+ channels. Quantitative electron microscope autoradiography revealed preferential, irregularly spaced labeling of the axolemma of neurosecretory axons, with a significantly higher crude specific activity than any other neuronal or non-neuronal compartment. The number of specific binding sites at the neural lobe surface was calculated to be about 23 per microns2 of axolemma.

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