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Comparative Study
. 1983 Feb;80(4):931-4.
doi: 10.1073/pnas.80.4.931.

Crystallization of a common cold virus, human rhinovirus 14: "isomorphism" with poliovirus crystals

J W Erickson, E A Frankenberger, M G Rossmann, G S Fout, K C Medappa, R R Rueckert
Comparative Study

Crystallization of a common cold virus, human rhinovirus 14: "isomorphism" with poliovirus crystals

J W Erickson et al. Proc Natl Acad Sci U S A. 1983 Feb.

Abstract

Crystals of rhinovirus 14 have been grown reproducibly. They diffract x-rays to a resolution of at least 3.5 A. The orthorhombic crystal unit cell contains two virions, each situated on a crystallographic twofold axis. At less than 30-A resolution, the space group approximates to 1222 with the particles possessing 222 pseudo crystallographic symmetry. The crystals are "isomorphous" with type I polio crystals [Finch, J. T. & Klug, A. (1959) Nature (London) 183, 1709-1714; Hogle, J. M. (1982) J. Mol. Biol. 160, 663-668], suggesting some similarities of structure between enteroviruses and rhinoviruses.

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