The regulation of testicular function

Abstract

From this review it is evident that our understanding of the control of testicular function has advanced greatly over the past decade. Many of the advances have depended on techniques to isolate and study the function of Sertoli cells and Leydig cells. Although this knowledge has been essential, it is important to proceed cautiously in the extrapolation of this information to the in vivo situation. The likely interdependence of the two compartments of the testis in normal function highlights the need to consider the testis as a whole, and future studies must give cognizance to this concept. Furthermore, the importance of blood and lymphatic flow and the evidence of hormonal influences on the vasculature of the testis add yet another dimension to the in vivo function of this organ.