doi: 10.1016/0014-5793(83)80569-9.
Stimulation by thyrotropin and cyclic AMP of the proliferation of quiescent canine thyroid cells cultured in a defined medium containing insulin
- PMID: 6305722
- DOI: 10.1016/0014-5793(83)80569-9
Item in Clipboard
Stimulation by thyrotropin and cyclic AMP of the proliferation of quiescent canine thyroid cells cultured in a defined medium containing insulin
FEBS Lett.
.
Free article
Abstract
We have developed serum-free primary cultures of differentiated follicular dog thyroid cells which allow the study of the hormonal control of cell proliferation. The cooperation of insulin and increasing cellular cyclic AMP by thyrotropin triggers the DNA synthesis and the proliferation. Dog thyroid cells are an example of a system in which cyclic AMP is a sufficient signal to stimulate the proliferation in quiescent cells.
Similar articles
-
Induction of DNA synthesis in dog thyrocytes in primary culture: synergistic effects of thyrotropin and cyclic AMP with epidermal growth factor and insulin.J Cell Physiol. 1987 Jan;130(1):58-67. doi: 10.1002/jcp.1041300110. J Cell Physiol. 1987. PMID: 3027108
-
Involvement of cyclic AMP, iodide and metabolites of arachidonic acid in the regulation of cell proliferation of isolated porcine thyroid follicles.Mol Cell Endocrinol. 1985 Sep;42(2):145-55. doi: 10.1016/0303-7207(85)90102-9. Mol Cell Endocrinol. 1985. PMID: 2998905
-
Factors controlling proliferation and differentiation of canine thyroid cells cultured in reduced serum conditions: effects of thyrotropin, cyclic AMP and growth factors.Mol Cell Endocrinol. 1984 Jun;36(1-2):79-93. doi: 10.1016/0303-7207(84)90087-x. Mol Cell Endocrinol. 1984. PMID: 6086426
-
The TSH cyclic AMP cascade in the control of thyroid cell proliferation: the story of a concept.Thyroidology. 1991 Dec;3(3):97-101. Thyroidology. 1991. PMID: 1726932 Review.
-
Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors.Physiol Rev. 1992 Jul;72(3):667-97. doi: 10.1152/physrev.1992.72.3.667. Physiol Rev. 1992. PMID: 1320763 Review. No abstract available.
Cited by
-
Cell-specific cyclic AMP-mediated induction of the PDGF receptor.EMBO J. 1990 Mar;9(3):915-20. doi: 10.1002/j.1460-2075.1990.tb08189.x. EMBO J. 1990. PMID: 1690127 Free PMC article.
-
Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation.Mol Biol Cell. 2008 Nov;19(11):4814-25. doi: 10.1091/mbc.e08-06-0617. Epub 2008 Sep 17. Mol Biol Cell. 2008. PMID: 18799615 Free PMC article.
-
Evidence supporting the identity in Graves' disease of thyroid-stimulating antibody and thyroid growth-promoting immunoglobulin G as assayed in FRTL5 cells.J Clin Invest. 1988 Mar;81(3):879-84. doi: 10.1172/JCI113398. J Clin Invest. 1988. PMID: 2893811 Free PMC article.
-
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice.Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1615-20. doi: 10.1073/pnas.1015557108. Epub 2011 Jan 10. Proc Natl Acad Sci U S A. 2011. PMID: 21220306 Free PMC article.
-
Differentiation expression during proliferative activity induced through different pathways: in situ hybridization study of thyroglobulin gene expression in thyroid epithelial cells.J Cell Biol. 1990 Aug;111(2):663-72. doi: 10.1083/jcb.111.2.663. J Cell Biol. 1990. PMID: 2199463 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
