doi: 10.1016/s0022-2836(83)80043-6.
Production of positively supercoiled DNA by netropsin
- PMID: 6306251
- DOI: 10.1016/s0022-2836(83)80043-6
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Production of positively supercoiled DNA by netropsin
J Mol Biol.
.
Abstract
The antibiotic netropsin binds to DNA by a non-intercalative mechanism. It increases the linking number of DNA so that in the presence of topoisomerase I, positively supercoiled molecules are produced.
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