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. 1983 Jun 15;167(1):211-6.
doi: 10.1016/s0022-2836(83)80043-6.

Production of positively supercoiled DNA by netropsin

G Snounou, A D Malcom

Production of positively supercoiled DNA by netropsin

G Snounou et al. J Mol Biol. .

Abstract

The antibiotic netropsin binds to DNA by a non-intercalative mechanism. It increases the linking number of DNA so that in the presence of topoisomerase I, positively supercoiled molecules are produced.

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