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. 1983 Jun 27:408:556-66.
doi: 10.1111/j.1749-6632.1983.tb23272.x.

The fibrinogen-dependent pathway of platelet aggregation

G A Marguerie, E F Plow

The fibrinogen-dependent pathway of platelet aggregation

G A Marguerie et al. Ann N Y Acad Sci. .

Abstract

Fibrinogen participates in platelet aggregation induced by ADP and this participation is receptor mediated. The role of fibrinogen in platelet function is not restricted to the ADP stimulus as the molecule may regulate aggregation induced by the direct interaction of the protein with a single, specific receptor system. Thus, a common fibrinogen-dependent mechanism leading to platelet aggregation is hypothesized.

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