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. 1983 Aug 15;39(8):894-6.
doi: 10.1007/BF01990425.

Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?

E Borda, L Sterin-Borda, M F Gimeno, M Lazzari, A L Gimeno

Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?

E Borda et al. Experientia. .

Abstract

The influence of methoxamine on the contractile tension of isolated rat abdominal aorta, and on its capacity to produce a platelet antiaggregating substance, were explored. Methoxamine stimulated platelet antiaggregation and diminished arterial tone. The last action was blocked by phentolamine as well as by inhibitors of cyclo-oxygenase and prostacyclinsynthetase.

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