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Comparative Study
. 1983 Aug;41(2):837-40.
doi: 10.1128/iai.41.2.837-840.1983.

Susceptibility of blood-derived monocytes and macrophages to caprine arthritis-encephalitis virus

L W Anderson, P Klevjer-Anderson, H D Liggitt
Comparative Study

Susceptibility of blood-derived monocytes and macrophages to caprine arthritis-encephalitis virus

L W Anderson et al. Infect Immun. 1983 Aug.

Abstract

Permissiveness of blood-derived caprine monocytes to infection by caprine arthritis-encephalitis virus increased during in vitro cultivation and differentiation into macrophages, as evidenced by immunofluorescence and release of extracellular infectious virus. The degree of cell susceptibility to virus infection varied among individual goats, independent of age or breed. Caprine arthritis-encephalitis virus infection of macrophages in vitro resulted in no alteration of five characteristic functional activities.

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