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. 1983;190(3):390-3.
doi: 10.1007/BF00331064.

Superunstable alleles at the cut locus in Drosophila melanogaster

T I Gerasimova

Superunstable alleles at the cut locus in Drosophila melanogaster

T I Gerasimova. Mol Gen Genet. 1983.

Abstract

This is a detailed study of the reversions of the ctMR2 allele putatively carrying á mobile element (MR-transposon) in the cut locus. Stable, unstable and superunstable revertants have been identified. Besides, a series of multiple unstable visible and lethal ct mutations derived from the ctMR2 allele have been obtained. They are shown to include supermutable alleles. The results suggest that the MR-transposon is connected with at least three functions: excision; change of orientation; and change of position within the cut locus, these functions being disturbed in different ways in different unstable ct+ and ct alleles. In some cases the mutant transitions are somehow strongly stimulated leading to superinstability, reaching the rate of 0.5.

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References

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