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. 1983 Jul 25;11(14):4835-52.
doi: 10.1093/nar/11.14.4835.

A repetitive and apparently transposable DNA sequence in Dictyostelium discoideum associated with developmentally regulated RNAs

S Chung, C Zuker, H F Lodish
Free PMC article

A repetitive and apparently transposable DNA sequence in Dictyostelium discoideum associated with developmentally regulated RNAs

S Chung et al. Nucleic Acids Res. .
Free PMC article

Abstract

Dictyostelium discoideum AX3 genomic DNA contains about 40 copies of a 4.5 Kb sequence. Each has the same restriction map, suggesting that they are all very similar. The sequences are scattered throughout the genome, and each of the six representative copies we cloned have different flanking sequences. Partial fragments of the 4.5 Kb sequence also are scattered throughout the genome. The DNA sequences flanking the 4.5 Kb repetitive sequences are different in different strains of Dictyostelium suggesting that the 4.5 Kb sequence is a transposable element. Each sub-region of this 4.5 Kb sequence is associated with a large number of mRNAs, all of which are developmentally regulated, but whose function is not known.

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References

    1. Nature. 1975 Apr 3;254(5499):431-2 - PubMed
    1. J Mol Biol. 1976 Apr 25;102(4):831-52 - PubMed
    1. Science. 1977 Apr 8;196(4286):180-2 - PubMed
    1. Cell. 1979 Apr;16(4):739-51 - PubMed
    1. Cell. 1979 Jun;17(2):415-27 - PubMed

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