Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1983 Aug 25;11(16):5629-43.
doi: 10.1093/nar/11.16.5629.

The nucleotide sequence of poliovirus type 3 leon 12 a1b: comparison with poliovirus type 1

G Stanway, A J Cann, R Hauptmann, P Hughes, L D Clarke, R C Mountford, P D Minor, G C Schild, J W Almond
Free PMC article
Comparative Study

The nucleotide sequence of poliovirus type 3 leon 12 a1b: comparison with poliovirus type 1

G Stanway et al. Nucleic Acids Res. .
Free PMC article

Abstract

The complete nucleotide sequence of the genome of the Sabin vaccine strain of poliovirus type 3 (P3/Leon 12 a1 b) has been determined from cDNA cloned in E. coli. The genome comprises a 5' non-coding region of 742 nucleotides, a large open reading frame of 6618 nucleotides (89% of the sequence) and a 3' non-coding region of 72 nucleotides. There is 77.4% base-sequence homology and 89.6% predicted amino-acid homology between types 1 and 3. Conservation of all glutamine-glycine and tyrosine-glycine cleavage sites suggests a mechanism of polyprotein processing similar to that established for poliovirus type 1.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1968 Sep;61(1):77-84 - PubMed
    1. Proc Natl Acad Sci U S A. 1982 Oct;79(19):5793-7 - PubMed
    1. Virology. 1973 Nov;56(1):400-3 - PubMed
    1. Proc Natl Acad Sci U S A. 1976 Feb;73(2):327-30 - PubMed
    1. Nucleic Acids Res. 1976 Sep;3(9):2387-98 - PubMed

Publication types

Associated data