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. 1983 Aug 1;213(2):555-7.
doi: 10.1042/bj2130555.

The fatty acid composition of 1,2-diacylglycerol and polyphosphoinositides from human erythrocyte membranes

D Allan, S Cockcroft

The fatty acid composition of 1,2-diacylglycerol and polyphosphoinositides from human erythrocyte membranes

D Allan et al. Biochem J. .

Abstract

The fatty acid compositions of 1,2-diacylglycerol and polyphosphoinositides have been determined in human erythrocyte membranes that have been incubated in the presence or in the absence of Ca2+. The results show that the diacylglycerol that is formed in Ca2+-treated membranes has a fatty acid composition closely similar to that of the inositides, consistent with previous indications that Ca2+ stimulates the activity of a polyphosphoinositide phosphodiesterase in the membranes. In contrast with some previous results, it appears that these plasma-membrane inositides and their derived diacylglycerols are rich in stearic acid and arachidonic acid.

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