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. 1983 Oct 17;162(2):390-5.
doi: 10.1016/0014-5793(83)80793-5.

Complete amino acid sequence of human T-cell leukemia virus structural protein p15

T D Copeland, S Oroszlan, V S Kalyanaraman, M G Sarngadharan, R C Gallo
Free article

Complete amino acid sequence of human T-cell leukemia virus structural protein p15

T D Copeland et al. FEBS Lett. .
Free article

Abstract

The complete amino acid sequence of human T-cell leukemia virus (HTLV) structural protein p15 has been determined. The intact protein and peptides generated by enzymatic digestion and acid cleavage were purified by reversed-phase liquid chromatography and subjected to semi-automated Edman degradation. HTLV p15 is a basic linear polypeptide composed of 85 amino acids with Mr 9458. The primary structure indicates that HTLV p15 is homologous to the nucleic acid binding proteins of other type-C retroviruses and especially related to bovine leukemia virus p12.

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