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. 1976 Oct;17(4):258-62.
doi: 10.1111/j.1600-0609.1976.tb01183.x.

Heparin cofactor activity and antithrombin III concentration in plasma related to age and sex

O R Odegärd, M K Fagerhol, M Lie

Heparin cofactor activity and antithrombin III concentration in plasma related to age and sex

O R Odegärd et al. Scand J Haematol. 1976 Oct.

Abstract

Heparin cofactor activity and antithrombin III (At-III) concentration were measured in plasma from 219 healthy men and 177 women. Narrow ranges for heparin cofactor activity and At-III concentration were found. The standard deviation for heparin cofactor activity in men and women was 8.6 and 10.1, respectively, for At-III concentration 10.4 and 12.5. In men, mean heparin cofactor activity and mean At-III concentration decreased significantly with increasing age. In women, mean heparin cofactor activity and mean At-III concentration tended to be lower in fertile age. Hereditary At-III deficiency was detected in one individual.

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