Case Reports
doi: 10.1111/j.1399-0004.1983.tb00076.x.
Characterization of a Y/15 translocation by banding methods, distamycin A treatment of lymphocytes and DNA restriction endonuclease analysis
- PMID: 6315280
- DOI: 10.1111/j.1399-0004.1983.tb00076.x
Item in Clipboard
Case Reports
Characterization of a Y/15 translocation by banding methods, distamycin A treatment of lymphocytes and DNA restriction endonuclease analysis
Clin Genet.
1983 Oct.
Abstract
A de novo 14/21 Robertsonian translocation and a familially inherited Y/15 translocation were observed in a male infant with anomalies of the external genitalia. The Y/15 translocation was confirmed by cultivating lymphocytes in a medium containing distamycin A and by determining the occurrence of the Y-specific DNA sequences by means of Hae III restriction endonuclease analysis. Any connection between the structural chromosomal abnormalities and the symptoms of the infant is highly improbable.
Similar articles
-
Use of repetitive DNA for diagnosis of chromosomal rearrangements.Hum Genet. 1983;64(4):339-42. doi: 10.1007/BF00292365. Hum Genet. 1983. PMID: 6311727
-
The identification of Y chromosome translocations following Distamycin A treatment.Clin Genet. 1981 May;19(5):335-42. doi: 10.1111/j.1399-0004.1981.tb00720.x. Clin Genet. 1981. PMID: 7197598
-
Demonstration of Y/autosomal translocations using distamycin A.Hum Genet. 1979;53(1):107-9. doi: 10.1007/BF00289459. Hum Genet. 1979. PMID: 535895
-
Minute chromosomes replacing the Y chromosome carry Y-specific sequences by restriction fragment analysis and in situ hybridization.Am J Med Genet. 1985 Oct;22(2):361-74. doi: 10.1002/ajmg.1320220221. Am J Med Genet. 1985. PMID: 2996350 Review.
-
Molecular detection of a translocation (Y;11) (q11.2;q24) in a 45,X male with signs of Jacobsen syndrome.Hum Genet. 1992 Mar;88(6):661-7. doi: 10.1007/BF02265294. Hum Genet. 1992. PMID: 1551671 Review.
Cited by
-
Satellited Y chromosomes: structure, origin, and clinical significance.Hum Genet. 1984;67(1):72-85. doi: 10.1007/BF00270562. Hum Genet. 1984. PMID: 6745929
-
Molecular characterization of a Y;15 translocation segregating in a family.Hum Genet. 1988 May;79(1):29-35. doi: 10.1007/BF00291705. Hum Genet. 1988. PMID: 3366460
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
