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Case Reports
. 1983 Oct;24(4):234-9.
doi: 10.1111/j.1399-0004.1983.tb00076.x.

Characterization of a Y/15 translocation by banding methods, distamycin A treatment of lymphocytes and DNA restriction endonuclease analysis

M Schmid, J Schmidtke, K Kruse, M Tolksdorf
Case Reports

Characterization of a Y/15 translocation by banding methods, distamycin A treatment of lymphocytes and DNA restriction endonuclease analysis

M Schmid et al. Clin Genet. 1983 Oct.

Abstract

A de novo 14/21 Robertsonian translocation and a familially inherited Y/15 translocation were observed in a male infant with anomalies of the external genitalia. The Y/15 translocation was confirmed by cultivating lymphocytes in a medium containing distamycin A and by determining the occurrence of the Y-specific DNA sequences by means of Hae III restriction endonuclease analysis. Any connection between the structural chromosomal abnormalities and the symptoms of the infant is highly improbable.

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